Contrast‑enhanced ultrasound imaging of the liver: a review of the clinical evidence for SonoVue and Sonazoid

May 18, 2020 — Abdominal Radiology Abstract Contrast-enhanced ultrasound (CEUS) has become an established modality in various clinical indications for liver diseases. SonoVue®, a pure blood pure agent, and Sonazoid®, which exhibits an additional Kupffer phase, are contrast agents approved for liver imaging. This review discusses and compares the current clinical evidence for these two […]

Ultrasound Enhancing Agents In the COVID-19 Era: Protocols, Safety, & Impact

Webinar – Northwest Imaging Forums (CME credits available – see below) Presented by: Jonathan R. Lindner1, Thomas R. Porter2, Michelle Bierig3 1. Oregon health and Sciences University; 2. University of Nebraska Medical Center; 3. Hillcrest Hospital South The current COVID-19 pandemic has raised interest in whether there are changes in either the role or safety […]

Registry on Performance of contrast echocardiography in confirmed COVID-19 patients

European Association of Cardiovascular Imaging (EACVI) Echocardiography is often used for the detection of cardiac dysfunction and identification of LV thrombus induced by COVID-19. However, there is no data regarding the usefulness and safety of echo contrast in COVID-19 patients. This registry has been designed to answer this crucial issue. You are kindly asked to […]

Contrast-Enhanced Ultrasound for the Evaluation of Renal Transplants

May 15, 2020 — Journal of Ultrasound in Medicine Abstract Contrast-enhanced ultrasound has emerged as a useful imaging modality for the evaluation of the transplant kidney. Advantages over traditional imaging modali¬ties such as computed tomography and magnetic resonance imaging include the ability to visualize a lesion’s enhancement pattern in real time, the lack of neph-rotoxicity, […]

Filling of Fine and Core Biopsy Needles With the Contrast Agent Sulfur Hexafluoride

Ex Vivo and in vitro Evaluation of Ultrasound Needle Visibility May 12, 2020 — Journal of Ultrasound in Medicine Abstract Objectives To investigate whether the ex vivo and in vitro ultrasound visibility of fine needles (FNs) and core biopsy needles (CNBs) can be improved by filling them with an ultrasound contrast agent. Methods After needle […]

Contrast‐Enhanced Ultrasound in Patients With COVID‐19

Pneumonia, Acute Respiratory Distress Syndrome, or Something Else? May 12, 2020 — Journal of Ultrasound in Medicine Abstract Coronavirus disease 2019 spiepr132 (COVID‐19) represents a very heterogeneous disease. Some aspects of spiepr132 COVID‐19spiepr132 pneumonia question the real nature of ground glass opacities and its consolidative lesions. It has been hypothesized that spiepr132 COVID‐19spiepr132 lung involvement […]

Real time ultrasound molecular imaging of prostate Cancer with PSMA-targeted Nanobubbles

Apr 26, 2020 — Nanomedicine Abstract Contrast-enhanced ultrasound with microbubbles has shown promise in detection of prostate cancer (PCa), but sensitivity and specificity remain challenging. Targeted nanoscale-contrast agents with improved capability to accumulate in tumors may result in prolonged signal enhancement and improved detection of PCa with ultrasound. Here we report nanobubbles (NB) that specifically […]

Sonothrombolysis Improves Myocardial Dynamics and Microvascular Obstruction Preventing Left Ventricular Remodeling in Patients With ST Elevation Myocardial Infarction

April 23, 2019 — American Heart Association Abstract Background: It has recently been demonstrated that high-energy diagnostic transthoracic ultrasound and intravenous microbubbles dissolve thrombi (sonothrombolysis) and increase angiographic recanalization rates in patients with ST-segment–elevation myocardial infarction. We aimed to study the effect of sonothrombolysis on the myocardial dynamics and infarct size obtained by real-time myocardial […]

Benefits, Open Questions and Challenges of the use of Ultrasound in the COVID-19 pandemic era

The views of a panel of worldwide international experts European Journal of Ultrasound – Ultraschall in der Medizin Authors: Fabio Piscaglia*, Federico Stefanini, Vito Cantisani, Paul S. Sidhu, Richard Barr, Annalisa Berzigotti, Maria Cristina Chammas, Jean-Michel Correas, Christopher Frank Dietrich, Steven Feintstein, Pintong Huang, Chrisitan Jenssen, Yuko Kono, Masatoshi Kudo, Ping Liang, Andrej Lyshchik, Christian […]

Lung Ultrasound in COVID-19 Webinar

April 14, 2020 — EFSUMB Presenters: F. Piscaglia, F. Stefanini, V. Salvatore To view webinar presentations, go to: http://www.efsumb.org/blog/webinar-covid19-pp Presentations: INTRODUCTION ON THE CLINICAL PICTURE OF COVID-19 DISEASE. BASIC CONCEPTS IN LUNG ULTRASOUND – FOCUS ON “US INTERSTITIAL SYNDROME” CHARACTERISTICS OF US PATTERN OF COVID-19 PNEUMONITIS USE OF US IN THE EMERGENCY DEPARTMENT DURING COVID-19 […]

The pediatric benefits of contrast enhanced ultrasound

April 20, 2020 — HealthCareBusiness News By Lauren Dubinsky, Senior Reporter In recent years, contrast-enhanced ultrasound (CEUS) has emerged as a novel way to image children for certain indications. Unlike CT, fluoroscopy and nuclear medicine, CEUS is free from radiation and doesn’t require sedation, which is often needed for pediatric patients undergoing MR. “This lack […]

First Protocol on How to Use Lung Ultrasound to Triage COVID-19

April 09, 2020 — EFSUMB By Liam Davenport The first protocol for the use of lung ultrasound to quantitively and reproducibly assess the degree of lung involvement in patients suspected of having COVID-19 infection has been published by a team of Italian experts with experience of using the technology on the front line. Particularly in […]

Ultrasound’s Role in Alzheimer’s Treatment Research

April 2, 2020 — Imaging technology News (ITN) By Katie Caron Editor at Scranton Gillette Communications An estimated 44 million people worldwide are currently living with Alzheimer’s disease, the most common form of dementia. About 5.8 million people in the United States live with the disease, where it is the sixth leading cause of death […]

Contrast-Enhanced Ultrasound of Focal Liver Masses: A Success Story

May 1, 2020 — ScienceDirect – Ultrasound in Medicine and Biology Abstract The epidemic of increasing fatty liver disease and liver cancer worldwide, and especially in Western society, has given new importance to non-invasive liver imaging. Contrast-enhanced ultrasound (CEUS) using microbubble contrast agents provides unique advantages over computed tomography (CT) and magnetic resonance imaging (MRI), […]

Use of CEUS LI-RADS for the Accurate Diagnosis of Nodules in Patients at Risk for Hepatocellular Carcinoma: A Validation Study

March 27, 2009 — Radiology: Imaging Cancer Abstract CEUS LI-RADS provided high specificity for noninvasive imaging-based diagnosis of hepatocellular carcinoma, removing the need for tissue diagnosis; in addition, it allowed for accurate categorization of all nodules encountered in patients at risk for hepatocellular carcinoma. Purpose To validate the contrast agent–enhanced US Liver Imaging Reporting and […]

CEUS of Focal Liver Masses: A Success Story!

The epidemic of increasing fatty liver disease and liver cancer worldwide, and especially in Western society, has given new importance to non-invasive liver imaging. Contrast-enhanced ultrasound (CEUS) using microbubble contrast agents provides unique advantages over computed tomography (CT) and magnetic resonance imaging (MRI), the currently established methods. Today, increased use of CEUS has provided safe […]

Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo

March 23, 2020 — ACS Sensors Abstract The key challenge for in vivo biosensing is to design biomarker-responsive contrast agents that can be readily detected and monitored by broadly available biomedical imaging modalities. While a range of biosensors have been designed for optical, photoacoustic and magnetic resonance imaging (MRI) modalities, technical challenges have hindered the […]

Ultrasound Mediated Destruction of LMW-HA-Loaded and Folate-Conjugated Nanobubble for TAM Targeting and Reeducation

March 23, 2020 — Dove Medical Press Abstract Purpose:  To synthesize and evaluate a novel folate-conjugated ultrasonic nanobubble (HA-FOL-NB) loading low-molecular-weight hyaluronic acid (LMW-HA) for specific tumor-associated macrophages (TAMs) targeting and reeducation. Methods:  The characteristics, cytotoxicity, contrast-enhanced ultrasound imaging (CEUS), and targeting ability to TAMs of HA-FOL-NBs were investigated. The TAMs reprogramming function of HA-FOL-NBs […]