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ICUS ANYTIME is a comprehensive CEUS education portal
offering the convenience of online learning and free CME credits.

Learn basic and advanced CEUS from the experts!

CLICK HERE for upcoming live webinars

CLICK HERE for upcoming bubble conferences and other CEUS programs

CLICK HERE for archived ICUS webinars.


ICUS VIRTUAL EXHIBITS simulate the traditional exhibit experience
offered at live, in-person educational programs.

See how ultrasound products are used to improve CEUS and patient care.

CLICK HERE to visit our Virtual Exhibit Booths.


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Global Contrast-Enhanced Ultrasound (CEUS)

Click on any country shaded in orange to see the commercially available agent(s). Zoom to see smaller countries.
 

(Agent(s) commercially available)

 

 

(No agent commercially available at this time)

 

* See package inserts for approved indications. Note that this “Global CEUS” map lists certain ultrasound contrast agents under different product names (i.e., Lumason/SonoVue and Definity/Luminity). ICUS will update this map as additional agents are approved throughout the world.

 

ICUS does not endorse or recommend the use of any ultrasound contrast agent or other medical product. In addition, ICUS does not warrant the accuracy of information provided in package inserts or herein. Medical decisions are the sole responsibility of health care providers and their patients, who are encouraged to carefully evaluate all potential risks and benefits associated with the use of any medical product or procedure including ultrasound contrast agents and (CEUS).


Building better bubbles for ultrasound could enhance image quality, facilitate treatments

Building better bubbles for ultrasound could enhance image quality, facilitate treatments

May 26, 2021 – By National Institute of Biomedical Imaging and Bioengineering
Read full text at: https://doi.org/10.1021/acsnano.0c09701
Newswise — Ultrasound is a non-invasive technique that uses sound waves to either generate images of tissues inside of the body, or to interact with tissues as a therapeutic tool – to break up gallstones, increase blood flow, or ablate tumors, for instance. Ultrasound contrast agents, which are typically tiny bubbles filled with gas, can enhance the reflection of ultrasound waves to improve the (read more…)

Contrast-Enhanced Ultrasonography–Based Hepatic Perfusion for Early Prediction of Prognosis in Acute Liver Failure

Contrast-Enhanced Ultrasonography–Based Hepatic Perfusion for Early Prediction of Prognosis in Acute Liver Failure

May 26, 2021 – Hepatology
Abstract
Background and Aims
Acute liver failure (ALF) is a rare but dramatic clinical syndrome characterized by massive hepatic necrosis leading to multiorgan failure. It is difficult to predict the outcomes in patients with ALF using existing prognostic models. We aimed to analyze hepatic perfusion using contrast-enhanced ultrasound and Doppler ultrasound in patients with ALF and investigate its utility as a prognostic biomarker.
Approach and Results
In this prospective observational study, 208 patients with acute liver injury/ALF were enrolled from (read more…)

Papillary breast lesions detected using conventional ultrasound and contrast-enhanced ultrasound: imaging characteristics and associations with malignancy

Papillary breast lesions detected using conventional ultrasound and contrast-enhanced ultrasound: imaging characteristics and associations with malignancy

May 21, 2021 – European Journal of Radiology
Abstract
Objective
This study aimed to evaluate the imaging features of papillary breast lesions detected using conventional ultrasonography (US) and contrast-enhanced ultrasound (CEUS) and to correlate the pathological results. Furthermore, the diagnostic efficiencies of these imaging features to predict the malignancy potential of papillary lesions were explored.
Methods
The findings of the conventional US and CEUS of 74 consecutive papillary breast lesions were assessed retrospectively. The obtained data were analyzed using univariate and multivariate logistic regressions to (read more…)

Delivering RNA therapies to brain tumors

Delivering RNA therapies to brain tumors

May 18, 2021 – NIH – Research Matters
By Sharon Reynolds
Ribonucleic acid, better known as RNA, is a workhorse molecule in the body. Different types of RNA do everything from helping produce proteins to regulating the activity (or expression) of genes.
Research into using RNA to treat diseases and disorders is expanding rapidly. RNA forms the backbone of several vaccines being used to prevent COVID-19. In the field of cancer research, scientists are interested in using RNA-based therapies to treat brain tumors, (read more…)

Impact of Contrast Echocardiography on Outcomes in Critically Ill Patients

Impact of Contrast Echocardiography on Outcomes in Critically Ill Patients

May 15, 2021 — American Journal of Cardiology
Limited data suggests ultrasound enhancing agent (UEA) use is associated with changes in clinical management and lower mortality in intensive care unit (ICU) patients. We conducted a retrospective observational study to determine if contrast echocardiography (vs non-contrast echocardiography) is associated with differences in length of stay (LOS) and subsequent resource utilization in the ICU setting.
The Premier Healthcare Database (Charlotte, NC) was analyzed to identify patients receiving Definity vs. no use of contrast during (read more…)

Application of Contrast-Enhanced Ultrasonography (CEUS) in the Assessment of Kidney Wound Recovery After Nephron-Sparing Surgery

Application of Contrast-Enhanced Ultrasonography (CEUS) in the Assessment of Kidney Wound Recovery After Nephron-Sparing Surgery

May 13, 2021 — Cancer Management and Research
Abstract
Purpose – To investigate feasibility, repeatability and usefulness of contrast-enhanced ultrasonography (CEUS) in the assessment of kidney wound recovery after laparoscopic nephron-sparing surgery (LNSS) or robot-assisted nephron-sparing surgery (RANSS) and preliminarily research the clinical factors associated with the length of extravasation (LOE).
Patients and Methods – From April 2019 to January 2020, 130 patients that underwent LNSS or RANSS in our hospital were included, and 90 patients (90/130) received CEUS examinations each one day (read more…)

Ultrasound organizations rally to support use of ultrasound contrast agents

Ultrasound organizations rally to support use of ultrasound contrast agents

May 12, 2021 — Reed Smith LLP
Following a recent warning from the US Food and Drug Administration (FDA) on the safety of certain ultrasound contrast agents (UCAs) containing polyethylene glycol (PEG), the American Institute of Ultrasound in Medicine (AIUM) joins the International Contrast Ultrasound Society (ICUS) in issuing a statement to reassure physicians and their patients that ultrasound contrast agents remain safe and beneficial for most patients.
Earlier, the FDA issued a notice that ultrasound contrast agents should not be administered (read more…)

Ultrasound societies say ‘no change’ to contrast agent policy

Ultrasound societies say ‘no change’ to contrast agent policy

May 11, 2021 — AuntMinnie.com
By Amerigo Allegretto, staff writer
No changes should be made to clinical guidelines on the use of ultrasound contrast agents in the wake of the U.S. Food and Drug Administration’s (FDA) recent statement on adverse reactions to contrast, according to statements made by a group of medical societies.
The American Institute of Ultrasound in Medicine (AIUM), the American Society of Echocardiography (ASE), and the International Contrast Ultrasound Society (ICUS) have issued statements in response to the FDA (read more…)

Medical Societies Support Safety and Benefits of Ultrasound Contrast Agents

Medical Societies Support Safety and Benefits of Ultrasound Contrast Agents

May 11, 2021 — Imaging Technology News (ITN)
The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke, identify and characterize tumors throughout the abdomen, and monitor the effectiveness of cancer therapies in (read more…)

Medical Societies Support Safety and Benefits of Ultrasound Contrast Agents

Medical Societies Support Safety and Benefits of Ultrasound Contrast Agents

May 10, 2021 — ICUS – Media Release
The American Institute of Ultrasound in Medicine (AIUM) and the American Society of Echocardiography (ASE) have joined the International Contrast Ultrasound Society (ICUS) in recognizing the relatively low risk and important clinical benefits of ultrasound contrast agents (UCAs), which are used routinely around the world to help detect heart disease, stratify the risk of heart attack or stroke, identify and characterize tumors throughout the abdomen, and monitor the effectiveness of cancer therapies in (read more…)