Global Contrast-Enhanced Ultrasound (CEUS)

Click on any country shaded in orange to see the commercially available agent(s).
 

(Agent(s) commercially available)

 

 

(No agent commercially available at this time)

 

* See package inserts for approved indications. Note that this “Global CEUS” map lists certain ultrasound contrast agents under different product names (i.e., Lumason/SonoVue and Definity/Luminity). ICUS will update this map as additional agents are approved throughout the world.

 

ICUS does not endorse or recommend the use of any ultrasound contrast agent or other medical product. In addition, ICUS does not warrant the accuracy of information provided in package inserts or herein. Medical decisions are the sole responsibility of health care providers and their patients, who are encouraged to carefully evaluate all potential risks and benefits associated with the use of any medical product or procedure including ultrasound contrast agents and (CEUS).


 

Can CEUS with second generation contrast agents replace CT angiography for distinguishing between occlusion and pseudo-occlusion of the internal carotid artery?

Can CEUS with second generation contrast agents replace CT angiography for distinguishing between occlusion and pseudo-occlusion of the internal carotid artery?

Clinics (Sao Paulo)
January, 2015
Carlos Augusto Pinto Ventura,I Erasmo Simão da Silva,II Giovanni Guido Cerri,I Pedro Puech Leão,IV Adriano Tachibana,I Maria Cristina ChammasIII
I Hospital das Clı´nicas da Faculdade de Medicina da Universidade de São Paulo, Department of Radiology, São Paulo/SP, Brazil. II Faculdade de Medicina da Universidade de São Paulo, Department of Surgery, São Paulo/SP, Brazil. III Hospital das Clı´nicas da Faculdade de Medicina da Universidade de São Paulo, Department of Ultrasound, São Paulo/SP, Brazil. IV Hospital das Clı´nicas da Faculdade (read more…)

Sound waves and microbubbles to tackle tumours

Sound waves and microbubbles to tackle tumours

The Times — November 13, 2019
By Rhys Blakely, Science Correspondent
Scientists have developed a means of using sound waves to track and manoeuvre tiny parcels of drugs to precise locations inside the body.
The technique could be used to ferry powerfully toxic cancer treatments to tumour sites, avoiding damage to surrounding tissues and dramatically reducing the amount of the drug to which the patient is exposed, researchers said.
It might also be used in gene therapies, where genetic material must reach and infiltrate (read more…)

Road to RSNA 2019: Ultrasound Preview

Road to RSNA 2019: Ultrasound Preview

November 11, 2019 — AuntMinnie.com
By Kate Madden Yee
What’s not to like about ultrasound? It’s cost-effective, portable, and noninvasive — and it’s proving to be an effective tool for a wide range of applications, from treating uterine fibroids and identifying hydrocephalus in children to diagnosing enlarged veins in patients with cirrhosis.
At this year’s RSNA meeting, ultrasound’s versatility will be on display via scientific presentations and posters, as well as refresher courses that will keep sonographers at the top of their (read more…)

CEUS predicts cirrhotic nodule transformation to HCC

CEUS predicts cirrhotic nodule transformation to HCC

Cirrhotic Nodule Transformation to Hepatocellular Carcinoma: Natural History and Predictive Biomarkers on Contrast-Enhanced Ultrasound
January 1, 2020 — American Journal of Roentgenology (AJR)
ABSTRACT :
OBJECTIVE. The objective of our study was to identify sonographic biomarkers predicting or indicating eventual malignant transformation of pathologically confirmed cirrhotic nodules.
MATERIALS AND METHODS. Thirty-nine consecutive patients with 44 pathologically confirmed cirrhotic nodules (mean size, 17.5 ± 8.5 [SD] mm) who initially underwent contrast-enhanced ultrasound examination at detection and then underwent follow-up conventional ultrasound every 3–4 months thereafter (read more…)

Higher prostate cancer targeting ability with multiparametric ultrasound

Higher prostate cancer targeting ability with multiparametric ultrasound

Automated multiparametric localization of prostate cancer based on B-mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics
European Radiology — October 10, 2019
Abstract
Objectives
The aim of this study was to assess the potential of machine learning based on B-mode, shear-wave elastography (SWE), and dynamic contrast-enhanced ultrasound (DCE-US) radiomics for the localization of prostate cancer (PCa) lesions using transrectal ultrasound.
Methods
This study was approved by the institutional review board and comprised 50 men with biopsy-confirmed PCa that were referred for radical prostatectomy. Prior to surgery, patients (read more…)

Can radiologists confidently use contrast-enhanced ultrasound LI-RADS?

Can radiologists confidently use contrast-enhanced ultrasound LI-RADS?

Health Imaging — October 8, 2019
By Matt O’Connor
Radiologists can confidently use the contrast-enhanced ultrasound liver imaging reporting and data system (CEUS LI-RADS) to categorize patients at high-risk for hepatocellular carcinoma (HCC), according to an Oct. 8 study published in the European Journal of Radiology.
Four ultrasound physicians used CEUS LI-RADS to rate the HCC likelihood of focal liver lesions (FLLs) in more than 1,000 patients. Upon analysis, first author Jia Wu Li and colleagues found the readers largely agreed on CEUS (read more…)

Ultrasound Imaging Finally Gets an Upgrade As Scientists Improve the Quality by 10x

Ultrasound Imaging Finally Gets an Upgrade As Scientists Improve the Quality by 10x

Oct 5, 2019 – Good News Network
Scientists have unveiled a new technique using a super-resolution ultrasound method that improves resolution by 5 to 10 times compared to standard ultrasound images.
The procedure, which allows whole organs to be scanned in super-resolution for the first time, is expected to lead to earlier cancer diagnoses and allow medical staff to more effectively target treatments to any malignant tissue. In fact, it could eventually replace the need for biopsy altogether.
Writing in the Journal of (read more…)

Ultrasound breakthrough ‘can spot cancer earlier’

Ultrasound breakthrough ‘can spot cancer earlier’

Sep 30, 2019 – BBC Scotland
By Kenneth Macdonald, BBC Scotland Science Correspondent
A new ultrasound technique is being hailed as the biggest breakthrough in the technology for more than 60 years. Developed at Heriot-Watt University in Edinburgh, it produces images that are 10 times better than current scans.
Researchers believe its ability to precisely pinpoint tumours could one day replace biopsies in investigating suspected cancer cases. The method, which is about to begin trials in human patients, uses existing scanning equipment.
In 1958, (read more…)

ICUS meeting highlights CEUS research

ICUS meeting highlights CEUS research

September 6, 2019 — AuntMinnie.com staff writers
The benefits of contrast-enhanced ultrasound (CEUS) are being highlighted at the International Contrast Ultrasound Society (ICUS) Bubble Conference in Chicago.
Among many other presentations, ICUS is highlighting the following research delivered at the conference:

A team led by Dr. Dirk-André Clevert of the University of Munich safely performed CEUS scans in pregnant women with suspected liver tumors.
A group led by Dr. Misun Hwang of the Children’s Hospital of Philadelphia used CEUS to diagnose brain injuries (read more…)

Resolution of indeterminate MRI with CEUS in patients at high risk for hepatocellular carcinoma

Resolution of indeterminate MRI with CEUS in patients at high risk for hepatocellular carcinoma

August, 2019 — Abdominal Radiology
Abstract
Purpose
To show the contribution of CEUS to characterization of indeterminate MRI observations in high-risk patients for hepatocellular carcinoma (HCC).
Methods
From July to December 2015, 42 consecutive patients referred to CEUS with indeterminate MRI scans comprise our study cohort. There are 50 indeterminate nodule-like observations and 10 arterial phase hyperenhancing foci, suggest-ing pseudolesions/arterio-portal shunts. MRI and CEUS lesions are classified according to their enhancement features in all phases and Liver Imaging and Reporting Data System (LI-RADS) in a (read more…)