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ICUS ANYTIME is a comprehensive CEUS education portal
offering the convenience of online learning and free CME credits.

Learn basic and advanced CEUS from the experts!

CLICK HERE for upcoming live webinars

CLICK HERE for upcoming bubble conferences and other CEUS programs

CLICK HERE for archived ICUS webinars.


ICUS VIRTUAL EXHIBITS simulate the traditional exhibit experience
offered at live, in-person educational programs.

See how ultrasound products are used to improve CEUS and patient care.

CLICK HERE to visit our Virtual Exhibit Booths.


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Global Contrast-Enhanced Ultrasound (CEUS)

Click on any country shaded in orange to see the commercially available agent(s). Zoom to see smaller countries.
 

(Agent(s) commercially available)

 

 

(No agent commercially available at this time)

 

* See package inserts for approved indications. Note that this “Global CEUS” map lists certain ultrasound contrast agents under different product names (i.e., Lumason/SonoVue and Definity/Luminity). ICUS will update this map as additional agents are approved throughout the world.

 

ICUS does not endorse or recommend the use of any ultrasound contrast agent or other medical product. In addition, ICUS does not warrant the accuracy of information provided in package inserts or herein. Medical decisions are the sole responsibility of health care providers and their patients, who are encouraged to carefully evaluate all potential risks and benefits associated with the use of any medical product or procedure including ultrasound contrast agents and (CEUS).


Researchers tout promise of contrast ultrasound at AIUM 2021

Researchers tout promise of contrast ultrasound at AIUM 2021

April 12, 2021 — AuntMinnie.com
By Amerigo Allegretto, staff writer
Contrast-enhanced ultrasound (CEUS) has a number of useful benefits over other forms of medical imaging, according to two studies presented Monday at the virtual 2021 American Institute of Ultrasound in Medicine (AIUM) annual meeting.
Researchers from Northwell North Shore and University Hospitals Cleveland Medical Center presented their respective findings on the uses of CEUS in interventional applications and vascular malformations, as well as other overall benefits of contrast ultrasound, such as better (read more…)

Value of Contrast-Enhanced Ultrasound in the Differential Diagnosis of Focal Splenic Lesions

Value of Contrast-Enhanced Ultrasound in the Differential Diagnosis of Focal Splenic Lesions

April 1, 2021 — Dovepress
Abstract
Purpose
To identify and validate contrast-enhanced ultrasound (CEUS) features for differentiating malignant from benign splenic lesions.
Patients and Methods
Splenic lesions in 123 patients who underwent conventional ultrasound (B-mode US) and CEUS were included in this study. Two radiologists evaluated the sonograms of B-mode and CEUS. Statistical analysis was performed to identify significant imaging predictors for splenic malignant lesions. Two other radiologists independently reviewed B-mode and CEUS sonograms and diagnosed the lesions based on proposed criteria as 1) benign, (read more…)

Medicare CY 2021 Coding & Payment for CEUS

Medicare CY 2021 Coding & Payment for CEUS

March 25, 2021 — ICUS
The CEUS Coding and Payment chart has recently been updated and is available on the ICUS website (icus-society.org). This chart may be copied and distributed freely to customers and colleagues. Click Here to view chart.

Contrast-Enhanced Ultrasonography Identifies Microperfusion in CKD

Contrast-Enhanced Ultrasonography Identifies Microperfusion in CKD

Mar 19, 2021 — Physician’s Weekly
“Renal perfusion plays an essential role in kidney health, as the kidneys receive up to 25% of cardiac output,” explains Menno Pruijm, PhD. “Although autoregulation mechanisms keep the perfusion of each kidney as constant as possible, acute reductions in global renal blood flow and disturbances in renal microcirculation (arterioles, capillaries, glomeruli)—such as that encountered during hypovolemic shock or sepsis—can lead to ischemia and acute kidney injury.”
In chronic conditions, Dr. Pruijm adds, stable hemodynamics are also (read more…)

Quadruple fusion imaging via transparent ultrasound transducer

Quadruple fusion imaging via transparent ultrasound transducer

March 16, 2021 — Pohang University of Science and Technology (POSTECH)
News Release – Research News
 
Schematic diagram of a quadruple fusion imaging system
A quadruple fusion optical and ultrasound imaging system has been developed that allows diagnosis of eye conditions or tumors or to see the environment inside the body using a transparent ultrasound transducer.
Professor Chulhong Kim of POSTECH’s Department of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, Dr. Byullee Park of Department of Convergence IT Engineering, Ph.D. candidate Jeongwoo Park (read more…)

Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients

Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients

March 15, 2021 — Nature Biomedical Engineering
Abstract
Changes in cerebral blood flow are associated with stroke, aneurysms, vascular cognitive impairment, neurodegenerative diseases and other pathologies. Brain angiograms, typically performed via computed tomography or magnetic resonance imaging, are limited to millimetre-scale resolution and are insensitive to blood-flow dynamics. Here we show that ultrafast ultrasound localization microscopy of intravenously injected microbubbles enables transcranial imaging of deep vasculature in the adult human brain at microscopic resolution and the quantification of haemodynamic parameters. Adaptive speckle (read more…)

Optimizing contrast‑enhanced echocardiography by employing a sonographer driven protocol

Optimizing contrast‑enhanced echocardiography by employing a sonographer driven protocol

March 13, 2021 — Journal of Echocardiography
Abstract
Background
The use of enhancing agents in echocardiography has been shown to facilitate improved study quality. Despite the known benefits, its use remains limited by institutional policies.
Methods
We aimed to retrospectively evaluate if allowing sonographers to place a peripheral intravenous catheter and administer enhancing agent led to a decrease in time to complete outpatient transthoracic echocardiograms in comparison to using nursing personnel. Three separate protocols were employed. The ‘nurse driven protocol’ utilized nurses to place a (read more…)

Tiny bubbles making large impact on medical ultrasound imaging

Tiny bubbles making large impact on medical ultrasound imaging

New research demonstrates ability to manipulate nanobubble size, acoustic resonance and, ultimately, ultrasound effectiveness — March 12, 2021
EurekAlert!
RYERSON UNIVERSITY – Faculty of Science
Research News – News release
 

Schematic of bubble membrane showing the influence of membrane stiffener and membrane softener in the phospholipid packing. Credit: Amin Jafari Sojahrood and Al C. de Leon
If you were given “ultrasound” in a word association game, “sound wave” might easily come to mind. But in recent years, a new term has surfaced: bubbles. Those ephemeral, (read more…)

An Update on the Pediatric CEUS Registry on Behalf of the “EFSUMB Pediatric CEUS Registry Working Group”

An Update on the Pediatric CEUS Registry on Behalf of the “EFSUMB Pediatric CEUS Registry Working Group”

March 9, 2021 — EFSUMB
Abstract
The European Federation of Ultrasound in Medicine and Biology (EFSUMB) created the “EFSUMB Pediatric Registry” (EFSUMB EPR) with the purpose of collecting data regarding the intravenous application of pediatric contrast-enhanced ultrasound (CEUS). The primary aim was to document the current clinical practice and usefulness of the technique and secondarily to assess CEUS safety in children. We issue the preliminary results of this database and examine the overall practice of CEUS in children in Europe.
Authors: Christoph F. (read more…)

Molecular imaging of orthotopic prostate cancer with nanobubble ultrasound contrast agents targeted to PSMA

Molecular imaging of orthotopic prostate cancer with nanobubble ultrasound contrast agents targeted to PSMA

February 25, 2021 — Sci Rep
Abstract
Ultrasound imaging is routinely used to guide prostate biopsies, yet delineation of tumors within the prostate gland is extremely challenging, even with microbubble (MB) contrast. A more effective ultrasound protocol is needed that can effectively localize malignancies for targeted biopsy or aid in patient selection and treatment planning for organ-sparing focal therapy. This study focused on evaluating the application of a novel nanobubble ultrasound contrast agent targeted to the prostate specific membrane antigen (PSMA-targeted NBs) (read more…)