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July 7, 2021 — AuntMinnie.com
By Staff writers
Parker Laboratories has led a consortium making an investment in Solstice Pharmaceuticals that’s designed to fund the company’s development of a new ultrasound contrast agent.
The agent is based on microbubble technology that allows image contrast to be precisely engineered and optimized with custom-made monodisperse microbubbles for use in a wide range of applications. It aims to enhance image contrast, improve diagnostic accuracy, and make ultrasound scanning more widely applicable.
Parker’s investment speeds up the (read more…)
Therapeutic Angiogenesis for Ovarian Transplantation through Ultrasound-Targeted Microbubble Destruction
July 1, 2021 — Ultrasound in Medicine and Biology
Timely angiogenesis and effective microcirculation perfusion are essential for the survival and functional recovery of transplanted ovaries. Ultrasound-targeted microbubble destruction (UTMD) can lead to angiogenesis and increase flow perfusion by causing transient inflammation. The purpose of this study was to evaluate the effects of UTMD on transplanted ovarian revascularization and survival. In vitro, for the criteria of cell viability and tube formation capability, the optimal exposure parameters were determined to be a (read more…)
Principal component regression-based contrast-enhanced ultrasound evaluation system for the management of BI-RADS US 4A breast masses: objective assistance for radiologists
July 1,2021 — Ultrasound in Medicine and Biology
A portion of detected breast masses might be overrated by using the Breast Imaging-Reporting and Data System ultrasonography (BI-RADS US) lexicon. A principal component regression-based contrast-enhanced ultrasound (PCR-CEUS) evaluation system was built to quantitatively illustrate whether CEUS could help radiologists to differentiate 4A masses. The PCR-CEUS evaluation system, based on principal component analysis (PCA) and logistic regression, was verified by random assignment into training and test sets and shown to reduce the data (read more…)
Free access to CEUS educational frameworks, webinars and other resources suitable for incorporation into the curricula of sonography training programs
Prepared by Joint Task Force on CEUS Curriculum in Sonographer Schools
July 1, 2021
Access the Hub at: www.icus-society.org
Contrast Enhanced Ultrasound (CEUS) has been an essential component of modern ultrasound laboratories throughout the world for over two decades. It is, therefore, imperative that sonography training programs incorporate CEUS education in their curricula.
To that end, the Joint Task Force on CEUS Curriculum in (read more…)
June 29, 2021 — DAIC
Echocardiography with ultrasound enhancing agents (UEAs) has proven to be a valuable imaging procedure after surgery for children born with single ventricle congenital heart disease (CHD). This heart defect occurs when one of the two ventricles is not large enough or strong enough to work correctly. Research presented at the American Society of Echocardiography (ASE) 2021 virtual meeting, June 18-21, highlights how echocardiography with UEAs in CHD patients post-operatively can improve diagnostic capabilities and decrease (read more…)
June 21, 2021 — DocWire News
Quantitative ultrasound (QUS) is a non-invasive imaging modality that permits the detection of tumor response following various cancer therapies. Based on ultrasound signal scattering from the biological system, scatterer size, and concentration of microscopic scatterers, QUS enables the rapid characterization of tumor cell death. In this study, tumor response to ultrasound-stimulated microbubbles (USMB) and hyperthermia (HT) in tumor-bearing mice, with prostate cancer xenografts (PC3), was examined using QUS. Treatment conditions included 1% (v/v) Definity microbubbles (read more…)
Predicting Long-Term Hepatocellular Carcinoma Response to Transarterial Radioembolization Using Contrast-Enhanced Ultrasound: Initial Experiences
June 13, 2021 — Ultrasound in Medicine and Biology
Conventional cross-sectional imaging done shortly after radioembolization of hepatocellular carcinoma (HCC) does not reliably predict long-term response to treatment. This study evaluated whether quantitative contrast-enhanced ultrasound (CEUS) can predict the long-term response of HCC to yttrium-90 (Y-90) treatment. Fifteen patients underwent CEUS at three time points: immediately following treatment and 1 and 2 wk post-treatment. Response 3–6 mo after treatment was categorized on contrast-enhanced magnetic resonance imaging by two experienced radiologists using (read more…)
Pediatric contrast-enhanced ultrasound: shedding light on the pursuit of approval in the United States
June 11, 2021 — Pediatric Radiology
For two decades, pediatric contrast US has been well accepted throughout Europe and other parts of the world outside the United States because of its high diagnostic efficacy and extremely favorable safety profile. This includes intravenous (IV) administration, contrast-enhanced US (CEUS) and the intravesical application, contrast-enhanced voiding urosonography (ceVUS). However, the breakthrough for pediatric contrast US in the United States did not come until 2016, when the U.S. Food and Drug Administration (FDA) approved the (read more…)
June 9, 2021 — DocWire News
Ultrasound is a non-invasive, real-time, inexpensive, radiation-free and easily repeatable method, usually used for liver imaging. In recent years, new ultrasound examination techniques for liver diseases such as contrast-enhanced ultrasound and elastography have been rapidly developed, which can effectively identify intrahepatic space-occupying lesions, assess the degree of liver fibrosis and portal hypertension, and monitor the effects of treatment. Therefore, these technologies play an important diagnostic role in clinical liver diseases and have therapeutic interventional value. (read more…)
June 3, 2021 — Scientific Reports
Microbubbles (MB) are widely used as contrast agents to perform contrast-enhanced ultrasound (CEUS) imaging and as acoustic amplifiers of mechanical bioeffects incited by therapeutic-level ultrasound. The distribution of MBs in the brain is not yet fully understood, thereby limiting intra-operative CEUS guidance or MB-based FUS treatments. In this paper we describe a robust platform for quantification of MB distribution in the human brain, allowing to quantitatively discriminate between tumoral and normal brain tissues and we (read more…)