Predictive Value of Contrast-Enhanced Ultrasound in Chemical Lumbar Sympathectomy for End-Stage Arteriosclerosis Obliterans of the Lower Extremities
January 15, 2022 — Pain Therapy Abstract Introduction The therapeutic effect of chemical lumbar sympathectomy (CLS) on ischemic diseases of the lower limbs varies greatly among individuals. The time to peak (TTP) response in contrast-enhanced ultrasound (CEUS) can reflect the perfusion disorder of the calf skeletal muscle and the collateral circulation. In this study we […]
Drug or Device? Manufacturers See Burden in FDA Reclassifying
January 11, 2022 — Bloomberg Law Authors: Celine Castronuovo Companies warn of reduced access to treatments Trade organizations ask FDA for input, clarity Patients could face disruptions in medical treatment if the FDA moves ahead with plans to regulate some products as devices instead of drugs, according to manufacturers who decry the shift as onerous […]
A new proposal for secondary surveillance following potentially curative therapy of HCC: alternating MRI and CEUS
January 8, 2022 Abstract Purpose A high recurrence rate following ablative therapy of hepatocellular carcinoma (HCC) necessitates routine follow-up imaging (secondary surveillance) to facilitate early re-treatment. We evaluate our unique secondary surveillance algorithm (with use of alternating MRI and CEUS) by assessment of the relative diagnostic accuracy of MRI and CEUS in detection of residual/recurrent […]
Subharmonic ultrasound better with contrast flow in breast masses
January 3, 2022 — AuntMinnie By: Amerigo Allegreto, stff writer Division of Cardiology, Peter Munk Cardiac Centre, Toronto General Hospital, Canada. Read full text at: https://doi.org/10.1016/j.echo.2021.07.015 Abstract 3D subharmonic ultrasound is better at detecting contrast flow in vascular breast masses than 3D harmonic ultrasound, according to research presented by Flemming Forsberg, PhD, at the RSNA […]
Routine Use of Contrast on Admission Transthoracic Echocardiography for Heart Failure Reduces the Rate of Repeat Echocardiography during Index Admission
December 31, 2021 — Journal of the American Society of Echocardiography Abstract Background The authors retrospectively evaluated the impact of ultrasound enhancing agent (UEA) use in the first transthoracic echocardiographic (TTE) examination, regardless of baseline image quality, on the number of repeat TTEs and length of stay (LOS) during a heart failure (HF) admission. Methods […]
Value of Contrast-Enhanced Ultrasound in Differentiating Clinically Atypical Subacute Thyroiditis from Papillary Thyroid Carcinomas
December 30, 2021 — Ultrasound in Medicine and Biology Abstract Our objective was to provide the various sonographic characteristics of clinically atypical subacute thyroiditis (CAST) in distinguishing CAST from papillary thyroid carcinomas (PTCs) by using conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS). Forty-six CAST patients and 50 PTC patients were enrolled in this study. We […]
Incidentally Detected Liver Metastases during Pancreas Contrast-enhanced Ultrasound
December 9, 2021 — Bio Integration Abstract Purpose The purpose of current study was to investigate the value of the late-phase enhancement features of pancreas contrast-enhanced ultrasound (CEUS) in the detection of liver metastases in patients with pancreatic ductal adenocarcinomas (PDAC). Methods From October 2020 to March 2021, 86 patients were prospectively enrolled. The gold […]
Left Ventricular Apical Aneurysms in Detection by Magnetic Resonance Imaging and Contrast Echocardiography
December 1, 2021 — Journal of the American Society of Echocardiology (JASE) Background Left ventricular (LV) apical aneurysm is a unique morphological entity and novel adverse risk marker existing within the broad phenotypic spectrum of hypertrophic cardiomyopathy (HCM). Its true prevalence in the HCM population is likely underestimated because of inherent limitations of conventional noncontrast […]
CEUS helps identify lymph nodes in breast cancer patients
November 30, 2021 – AuntMinnie Authors: Amerigo Allegretto, staff writer Contrast-enhanced ultrasound (CEUS) lymphosonography is useful in identifying sentinel lymph nodes in breast cancer patients undergoing surgery, according to research presented November 29 at the RSNA annual meeting. In her presentation, Dr. Priscilla Machado from Thomas Jefferson University in Philadelphia showed findings from […]
Quantitative Evaluation of Renal Cortex Perfusion Using Contrast-Enhanced Ultrasound Imaging Parameters in Ischemia–Reperfusion Injury in Rabbits
Abstract The aim of this study was to evaluate blood perfusion of the renal cortex during ischemia–reperfusion (I/R) injury using quantitative contrast-enhanced ultrasound (CEUS) parameters. In this experiment, 24 rabbits were randomly divided into four groups (N = 6): sham-operated group, 24-h post-operation for I/R injury group (24-h I/R), 3-d post-operation for I/R injury group […]
Contrast-Enhanced Ultrasound Patterns for the Non-invasive Diagnosis of Hepatocellular Carcinoma: A Prospective Multicenter Study in Histologically Proven Liver Lesions in a Real-Life Setting Demonstrating the Benefit of Extended Late Phase Observation
Abstract The hallmark for the non-invasive diagnosis of hepatocellular carcinoma (HCC) with contrast-enhanced ultrasound (CEUS) in cirrhosis is arterial phase hyperenhancement (APHE), followed by late-onset (>60 s), mild washout. Large retrospective studies report this pattern of washout to occur in the vast majority of HCCs. However, a prospective multicenter validation of these findings is still […]
Chemotherapy Augmentation Using Low-Intensity Ultrasound Combined with Microbubbles with Different Mechanical Indexes in a Pancreatic Cancer Model
Abstract The aim of the study was to explore the optimal mechanical indexes (MIs) for low-intensity ultrasound (LIUS) combined with microbubbles to enhance tumor blood perfusion and improve drug concentration in pancreatic cancer-bearing nude mice. Fifty-four nude mice bearing bilateral pancreatic tumors on the hind legs were randomly divided into three groups (the MI was […]
Reasons why referring doctors order renal ultrasound contrast studies
November 27, 2021 — Abdominal Radiology Abstract Purpose To determine the indications for CEUS for renal mass evaluation. Methods This retrospective, single-center, IRB-approved, HIPAA compliant study analyzed data from 303 consecutive patients scheduled for a renal CEUS to determine the indications for the examination. A chart review was performed from 05/01/2020 through 05/31/2021 on all […]
Contrast Enhanced Ultrasound Market | Rising Ultrasound Procedural Volume Projected to Boost Growth Opportunities
The contrast enhanced ultrasound market has been experiencing significant growth opportunities in the upcoming years. This market growth is on the back of growing ultrasound procedural volume, contrast imaging modes, and the onset of different affordable contrast agents. These modes are working as intrinsic features of the ultrasound systems. Owing to these factors, the contrast […]
Characteristics of contrast-enhanced ultrasound for diagnosis of solid clear cell renal cell carcinomas ≤4 cm: A meta-analysis
Abstract Now solid renal tumors ≤4 cm is the most common, especially the subtype of clear cell renal cell carcinoma (ccRCC) of malignant kidney tumors in clinical. However, there is not specific characteristics of contrast-enhanced ultrasound (CEUS) be recommended by the EFSUMB Guidelines in distinguish the essence of the kidney tumor with different sizes. Therefore, […]
Contrast-Enhanced Ultrasound in Children: Implementation and Key Diagnostic Applications
Abstract Contrast-enhanced ultrasound (CEUS) utilization is expanding rapidly, particularly in children, in whom the modality offers the important advantages of dynamic evaluation of the vasculature, portability, lack of ionizing radiation, and lack of need for sedation. Accumulating data establish an excellent safety profile of ultrasound contrast agents (UCAs) in children. Although UCAs have been FDA-approved […]
Contrast-enhanced ultrasound: a comprehensive review of safety in children
October 30, 2021 — Pediatric Radiology Abstract Contrast-enhanced ultrasound (CEUS) has been increasingly used in pediatric radiology practice worldwide. For nearly two decades, CEUS applications have been performed with the off-label use of gas-containing second-generation ultrasound contrast agents (UCAs). Since 2016, the United States Food and Drug Administration (FDA) has approved the UCA Luma-son for […]
Use of Contrast-Enhanced Ultrasound Sonography in Giant Cell Arteritis: A Proof-of-Concept Study
Abstract C-Reactive protein and erythrocyte sedimentation rate are crucial parameters used to monitor giant cell arteritis (GCA). Given that tocilizumab is approved for the treatment of GCA, these parameters are less sensitive because of the effects of interleukin-6 receptor blockade. Thus, the optimal method for monitoring GCA patients undergoing tocilizumab therapy, especially patients exhibiting a […]
Sound Waves Aid Brain Tumor Treatment — In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery.
A first-in-human trial reported in Science Translational Medicine today (October 13) demonstrates delivery of an immunotherapy drug to metastatic brain tumors with the help of focused ultrasound. The targeted low-frequency sound waves temporarily opened the normally impenetrable blood-brain barrier at the sites of tumors in stage 4 breast cancer patients, enabling drug entry. Follow up […]
Detecting insulitis in type 1 diabetes with ultrasound phase-change contrast agents
Abstract Type 1 diabetes (T1D) results from immune infiltration and destruction of insulin-producing β cells within the pancreatic islets of Langerhans (insulitis). Early diagnosis during presymptomatic T1D would allow for therapeutic intervention prior to substantial β-cell loss at onset. There are limited methods to track the progression of insulitis and β-cell mass decline. During insulitis, […]
