The Application of Contrast Enhanced Ultrasound for Core Needle Biopsy of Subpleural Pulmonary Lesions: Retrospective Analysis in 92 Patients
February 2, 2021 Abstract The purpose of this study was to investigate the role of contrast-enhanced ultrasound (CEUS) in determining the viable target area in patients with subpleural pulmonary lesions before ultrasound-guided transthoracic core biopsy. In this retrospective study, we analyzed 92 patients with subpleural pulmonary lesions (63 males and 29 females; mean age: 65.17 […]
Clinical Utility of Contrast-enhanced Ultrasound for the Diagnosis of Lymphadenopathy
January 21, 2021 — Ultrasound in Medicine and Biology Abstract This meta-analysis aimed to evaluate the diagnostic accuracy of contrast-enhanced ultrasonography (CEUS) in identifying lymphazdenopathy. PubMed, Web of Science, Embase and the Cochrane Library were searched for relevant articles through September 2020. A total of 16 articles, which included 1787 participants, were analyzed. The summary […]
Perfusion patterns of peripheral pulmonary lesions in COVID‐19 patients using contrast‐enhanced ultrasound (CEUS)
January 18, 2021 — Journal of Ultrasound in Medicine Abstract Purpose To describe perfusion patterns of peripheral pulmonary lesions (PPLs) in COVID‐19 patients using contrast‐enhanced ultrasound (CEUS). Patients and methods From April 2020 until July 2020, 11 consecutive patients with RT‐PCR‐confirmed COVID‐19 and PPLs sized over 5 mm were investigated by B‐mode ultrasound (B‐US) and CEUS. […]
Cortical perfusion as assessed with contrast-enhanced ultrasound is lower in patients with chronic kidney disease than in healthy subjects but increases under low salt conditions
January 11, 2021 — Nephrology Dialysis Transplantation Abstract Background Disturbances in renal microcirculation play an important role in the pathophysiology of chronic kidney disease (CKD), but the lack of easy accessible techniques hampers our understanding of the regulation of the renal microcirculation in humans. We assessed whether contrast-enhanced ultrasound (CEUS) can identify differences in cortical […]
New Applications in Echocardiography for Ultrasound Contrast Agents in the 21st Century
January 8, 2020 — Ultrasound in Medicine and Biology Abstract Contrast echocardiography microbubbles are ultrasound-enhancing agents that were originally designed to help improve endocardial border definition, known as left ventricle opacification, and to enhance Doppler signals. Over time, contrast microbubbles are used to assess myocardial perfusion because they travel through the capillaries of the cardiac […]
Microbubbles Augment RT in Liver Cancer Patients
December 31, 2020 — MedImaging.net By Staff writers A new study suggests that bursting gas-filled microbubbles using ultrasound waves sensitizes liver tumors to targeted radiation therapy (RT), improving overall survival. Researchers at Thomas Jefferson University (TJU; Philadelphia, PA, USA) conducted a pilot study involving 28 patients (mean age 70 years, 17 men) with hepatocellular carcinoma […]
Contrast-Enhanced Ultrasound Assessment of Renal Parenchymal Perfusion in Patients with Atherosclerotic Renal Artery Stenosis to Predict Renal Function Improvement After Revascularization
December 31, 2020 — International Journal of General Medicine Abstract Background: Identifying patients with atherosclerotic renal artery stenosis (ARAS) who will be improved in renal function after percutaneous transluminal renal artery stenting (PTRAS) is crucial since most patients show no worthwhile benefit of PTRAS. Although the assessment of renal parenchymal perfusion is useful for the […]
Prognostic value of intraplaque neovascularization detected by carotid Contrast-Enhanced Ultrasound in patients undergoing stress echocardiography
December 29, 2020 — Journal of the American Society of Echocardiography (JASE) Abstract Background Stress echocardiography (SE) is used for diagnosis and risk stratification of patients with known or suspected coronary artery disease (CAD). Contrast-enhanced ultrasound (CEUS) detects carotid intraplaque neovascularization (IPN). Objectives We hypothesized that combining SE with carotid CEUS in patients with known […]
Clinical and Contrast-enhanced Ultrasound Characteristics of Epithelioid and Classic Hepatic Angiomyolipoma: Comparison With Alpha-fetoprotein–negative Hepatocellular Carcinoma
December 19 , 2020 — Ultrasound in Medicine and Biology Abstract Hepatic angiomyolipoma (HAML) comprises epithelioid angiomyolipoma (EAML) and classic hepatic angiomyolipoma (CAML). The imaging appearance of HAML varies widely, and EAML is more easily misdiagnosed as hepatocellular carcinoma (HCC) than as CAML. The clinical and contrast-enhanced ultrasound (CEUS) features of CAML, EAML and HCC […]
Microbubbles Create Greater Radiation Sensitivity in Liver Tumors
December 15, 2020 — Diagnostic Imaging By Whitney J. Palmer Popping microbubbles with ultrasound waves prompts greater radiation susceptibility, leading to lower tumor growth and better long-term patient outcomes. Bursting gas bubbles next to liver tumors with ultrasound waves can improve the effect of radiation therapy, potentially leading to better overall survival. In a first-in-human […]
A first-in-human clinical trial shows microbubbles augments radiation in liver cancer patients
Bursting gas-filled microbubbles using ultrasound waves sensitizes tumors to targeted radiation, reducing tumor growth and improving overall survival after treatment December 15, 2020 — Thomas Jefferson University EurekAlert! News release Primary liver cancer is on the rise worldwide, largely due to an increase in hepatitis C infections and chronic liver disease. Liver cancer is also […]
US-triggered Microbubble Destruction for Augmenting Hepatocellular Carcinoma Response to Transarterial Radioembolization: A Randomized Pilot Clinical Trial
December 15, 2020 — Radiology Abstract Combined US-triggered microbubble destruction and hepatocellular carcinoma radioembolization showed improved treatment response compared with radioembolization alone and no changes in vital signs or liver function. Background US contrast agents are gas-filled microbubbles (MBs) that can be locally destroyed by using external US. Among other bioeffects, US-triggered MB destruction, also […]
Contrast-enhanced ultrasonography to evaluate risk factors for short-term and long-term outcomes after liver transplantation: A pilot prospective study
December 14, 2020 — European Journal of Radiology Abstract Purpose To evaluate whether Doppler ultrasonography (DUS) and contrast-enhanced ultrasonography(CEUS) can identify liver donation after brain death (DBD) and cardiac death (DCD)with the risk of developing short-term primary graft dysfunction (PGD) or arterialand biliary complications within 1 year. Materials and methods Consecutive DBD and DCD donors […]
Contrast-enhanced ultrasound of the liver in colorectal cancer: A useful tool in the right patient
December 10, 2020 — Journal of Hepatology Editorial Refers to: Contrast-enhanced ultrasound can guide the therapeutic strategy by improving the detection of colorectal liver metastases, Journal of Hepatology, October 14, 2020 Contrast-enhanced ultrasound (CEUS) was introduced around 20 years ago and hepatological applications have been the mainstay of its use since then. Several studies have […]
Should We Use Contrast-Enhanced Ultrasound (CEUS) for the Characterization of Nonpalpable Testicular Lesions? An Analysis from a Cost-Effectiveness Perspective
December 1, 2020 — Ultraschall in der Medizin – European Journal of Ultrasound Abstract Purpose Accurate characterization of testicular lesions is crucial to allow for correct treatment of malignant tumors and to avoid unnecessary procedures in benign ones. In recent years, contrast-enhanced ultrasound (CEUS) proved to be superior in specifying the dignity of small, nonpalpable […]
Recent Advances on Ultrasound Contrast Agents for Blood-Brain Barrier Opening with Focused Ultrasound
November 21, 2020 — Pharmaceutics – Special Issue: Advances in Physics Methods for Drug Delivery Abstract The blood-brain barrier is the primary obstacle to efficient intracerebral drug delivery. Focused ultrasound, in conjunction with microbubbles, is a targeted and non-invasive way to disrupt the blood-brain barrier. Many commercially available ultrasound contrast agents and agents specifically designed […]
Comparison Between Below Knee Contrast Enhanced Tomographic 3D Ultrasound and CT, MR or Catheter Angiography for Peripheral Artery Imaging
November 20, 2020 — European Journal of Vascular and Endovascular Surgery Abstract Objective Clear imaging of below knee and foot arteries is essential to plan distal reconstructions. Contrast enhanced tomographic 3D ultrasound (CEtUS) is novel and entirely safe with no exposure to ionising radiation or nephrotoxic contrast. In the present study, inter- and intra-observer agreement […]
Carotid Intraplaque Neovascularization on Contrast-Enhanced Ultrasound Correlates with Cardiovascular Events and Poor Prognosis: A Systematic Review and Meta-analysis
November 17, 2020 — Ultrasound in Medicine and Biology Abstract The goal of this meta-analysis is to investigate whether carotid intraplaque neovascularization (IPN) on contrast-enhanced ultrasound (CEUS) correlates with past cardiovascular events (CVEs) and prognosis. The present meta-analysis included 22 studies involving 3232 patients. The pooled analysis revealed that the presence of IPN was significantly […]
EMUC 2020: Ultrasound Is Improving: 29 Mhz, mpUS, C-TRUS, Elastography and Microbubble
November 16, 2020 — UroToday.com At the Fragments of Imaging session at the European Multidisciplinary Congress on Urological Cancers 2020 virtual meeting, Dr. Christophe Mannaerts discussed emerging roles for ultrasound as it relates to prostate cancer detection. Dr. Mannaerts started by noting that greyscale ultrasound is not a reliable method for detecting prostate cancer, even […]
Time Difference of Arrival on Contrast-Enhanced Ultrasound in Distinguishing Benign Inflammation From Malignant Peripheral Pulmonary Lesions
November 12, 2020 — Frontiers in Oncology Abstract Introduction: Worldwide, the incidence and mortality of lung cancer are at the highest levels, and the most lesions are located in the lung periphery. Despite extensive screening and diagnosis, the pathologic types of peripheral pulmonary lesions (PPLs) are difficult to diagnose by noninvasive examination. This study aimed […]
