Aug 16, 2018 –

Abstract

The optimal strategy for imaging after focal therapy for prostate cancer is evolving. This series is an initial report on the use of contrast-enhanced transrectal ultrasound (TRUS) in follow-up of patients after high-intensity focused ultrasound (HIFU) hemiablation for prostate cancer. In 7 patients who underwent HIFU hemiablation, contrast-enhanced TRUS findings were as follows: (1) contrast-enhanced TRUS clearly showed the HIFU ablation defect as a sharply marginated nonenhancing zone in all patients; (2) contrast-enhanced TRUS identified suspicious foci of recurrent enhancement within the ablation zone in 2 patients, facilitating image-guided prostate biopsy, which showed prostate cancer; and (3) contrast-enhanced TRUS findings correlated with multiparametric magnetic resonance imaging and biopsy histologic findings.

Authors: de Castro Abreu AL1, Ashrafi AN1, Gill IS1, Oishi M1, Winter MW1, Park D1, Duddalwar V2, Stern MC1,3, Palmer SL2, Aron M4, Gulati M2.

1USC Institute of Urology, University of Southern California, Los Angeles, California, USA.

2Department of Radiology, University of Southern California, Los Angeles, California, USA.

3Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

4Department of Pathology, University of Southern California, Los Angeles, California, USA

J Ultrasound Med. 2018 Aug 16. doi: 10.1002/jum.14765.