ICUS Weekly News Monitor 4-4-2018

1.  ICUS, CEUS Basic Training, Chicago Apr 21/22

2.  ILCA,  Mar 20, 2018,  Message from the ILCA President

3.  Ultrasound in Medicine and Biology,  Jan 29, 2018,  Meta-Analysis: Contrast Enhanced Ultrasound versus conventional Ultrasound for differentiation of benign and malignant breast lesions     Authors:  Qian Li, et al

CEUS "Basic Training"

 
 
 

ICUS is proud to expand its educational programs in 2018 to include practical training for successful use of contrast enhanced ultrasound (CEUS) of the cardiovascular system and abdomen.

Learn when and how to use CEUS to improve patient care, outcomes and workflows.

 
 
 

Chicago - April 21-22, 2018

Cardiac CEUS

 Saturday, April 21 - Willis Tower, Suite 5900, Chicago, IL 60606 

Steve Feinstein, MD- Professor, Rush University Medical Center; Program Host
Thomas Porter, MD- Chair of Cardiology, University of Nebraska
Joseph Petrusa, RDCS- Manager, Rush Echocardiology Laboratory
John Grabowski, BSN, RN- Nursing Supervisor, Rush Echocardiology Laboratory 

Abdominal CEUS

 Sunday, April 22 - Willis Tower, Suite 5900, Chicago, IL 60606 

Speaker: Richard Barr, MD, PhD 
Professor of Medicine, Northeast Ohio Medical University
Host: Stephanie Wilson, MD
Professor of Medicine, University of Calgary  

Registration

A $100 registration fee per training program includes program materials and meals.  Registration does not include transportation or lodging, which should be arranged by participants themselves. 

Students and trainees will receive a $50 refund after showing appropriate ID when checking in for the program. 

Online registration links: 

Program Description

To see full agendas and course descriptions, go to:icus-society.org/ceus-basic-training  

Expert lectures will address practical skills needed to implement a successful CEUS program, with multiple ultrasound systems and contrast agents available for participants to examine. Topics will include: 

  1. Microbubble contrast agents: Safety, uses, cost effectiveness. 
  2. Getting started: From set-up to injection to optimizing settings and performance.  
  3. Interpreting the images: Basic and advanced skills.
  4. CEUS economics:What you need to know about billing codes, and using CEUS to reduce the length of hospital stays and time to diagnosis. 
  5. Knobology– Break out rooms with personalized opportunities to "touch and feel" multiple ultrasound systems and contrast agents, examine settings, etc. 

Programs are suitable for physicians, sonographers, nurses, technicians, administrators, industry and others interested in CEUS. 

Location

Dentons US LLP
Willis Tower - 233 S Wacker Dr #5900, Chicago, IL 60606

*Use entrance on Adams Street.

Note: Classes will start promptly at 8am; to ensure on-time arrival, attendees should allow extra time for security and building navigation.

For additional information, please contact:

Stephanie Wilson, MD - This email address is being protected from spambots. You need JavaScript enabled to view it. This email address is being protected from spambots. You need JavaScript enabled to view it. , Steve Feinstein, MD -  This email address is being protected from spambots. You need JavaScript enabled to view it.

 
 
 
 
 
 

International Liver Cancer Association (ILCA)

Message from the ILCA President

Mar 20, 2018

Dear colleagues,

Worldwide interest in HCC continues to grow. In 2017 Pubmed recorded over 7000 articles in which HCC was a keyword. Of these about 10% were reviews. Of course, some of these publications were in low impact journals and would not be expected to change practice in any meaningful way. However, there was at last one major clinical advance, with positive results coming from the cabozantinib trial. There are now 5 agents that are either licensed or will be, that can be used for the management of HCC. The big question will be whether these agents can be combined and if so how should they be combined or used sequentially. On the basic science side, there were many articles exploring the genetics of HCC and the expression profile of these cancers. The tumour (and liver) microenvironment was also the subject of intensive investigation.

Non-alcoholic fatty liver disease has a complex relationship with hepatocellular carcinoma. Many investigators, both in the laboratory and in the clinic are trying to get to grips with these complexities to understand how fatty liver predisposes to HCC, and from a clinical standpoint, how to define who is at risk for HCC and how to provide surveillance. New surveillance algorithms that do not necessarily include ultrasonography are required.

Contrast ultrasound agents are now available in the USA, bringing ultrasound in the US into the 21st century. It is a mystery that contrast US has been widely available elsewhere for years, but only recently in the US. In response the LI-RADS group has developed specific reporting tools for liver masses interrogated by contrast ultrasound.

At ILCA, the Executive Committee is exploring new ways to improve our “product”, to provide more services to our members and to the liver cancer community in general. More on this in future columns as these projects move to fruition.

Best wishes and regards to all,

Morris Sherman

 
 
 
 
 
 

Ultrasound in Medicine and Biology

Meta-Analysis: Contrast Enhanced Ultrasound versus conventional Ultrasound for differentiation of benign and malignant breast lesions.

Jan 29, 2018

Vol. 44, No. 5, pp. 919–929, 2018

Authors: Qian Li,* Min Hu,† Zhikui Chen,‡ Changtian Li,§ Xi Zhang,¶ Yiqing Song,‖ and Feixiang Xiang**,††

* Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; † Department of Cardiovascular Surgery, Tongji Hospitial, Tongji Medical College, Huazhong University of Science and Technology,Wuhan, China; ‡ Department of Ultrasound, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China; § Department of Ultrasound, The Southern Building, Chinese PLA General Hospital, Beijing, China; ¶ Clinical Research Unit, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; ‖ Department of Epidemiology, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA; ** Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 JieFang Avenue,Wuhan 430022, China; and †† Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, 1277 JieFang Avenue,Wuhan 430022, China

Abstract

This meta-analysis aimed to compare the diagnostic performance of contrast-enhanced ultrasound (CEUS), conventional ultrasound (US) combined with CEUS (US + CEUS) and US for distinguishing breast lesions. From thorough literature research, studies that compared the diagnostic performance of CEUS versus US or US + CEUS versus US, using pathology results as the gold standard, were included. Atotal of 10 studies were included, of which 9 compared the diagnostic performance of CEUS and US, and 5 studies compared US + CEUS and US. In those comparing CEUS versus US, the pooled sensitivity was 0.93 (95% CI: 0.91–0.95) versus 0.87 (95% CI: 0.85–0.90) and pooled specificity was 0.86 (95% CI: 0.84–0.88) versus 0.72 (95% CI: 0.69–0.75). In studies comparing US + CEUS versus US, the pooled sensitivity was 0.94 (95% CI: 0.92–0.96) versus 0.87 (95% CI: 0.84–0.90) and pooled specificity was 0.86 (95% CI: 0.82–0.89) versus 0.80 (95% CI: 0.76–0.84). In terms of diagnosing breast malignancy, areas under the curve of the summary receiver operating characteristic (of both CEUS (p = 0.003) and US + CEUS (p = 0.000) were statistically higher than that of US. Both CEUS alone and US + CEUS had better diagnostic performance than US in differentiation of breast lesions, and US + CEUS also had low negative likelihood ratio.

 

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ICUS is the world’s only professional society exclusively devoted to contrast-enhanced ultrasound (CEUS) medical imaging technology.

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