Optison For Your Lab

Ordering Information

Optison is conveniently packaged in 3-mL vials for single-patient use, with five 3-mL vials per box. To place an order for Optison, please call GE Healthcare Customer Service at 800 292 8514 or contact your local GE Healthcare sales representative.

Reimbursement Information for Optison

Healthcare providers should use their best judgment in selecting the most appropriate codes to  eflect the services that they provide to their patients. Please refer to the most current professional coding reference books or Medicare’s coding guidelines for additional information.

Physicians performing echocardiography studies using Optison should report the HCPCS code for the drug and the CPT® code(s) for the procedure(s). The corresponding HCPCS codes are as follows:

HCPCS Codes for Optison

Some payers also may require the NDC for the product on the claims form:

  • NDC 0407-2707-03 Optison, 1 box, five 3-mL vials


All coding and reimbursement information is for reference purposes only. GE Healthcare does not guarantee payment. Use of information in this document does not ensure that you will successfully obtain insurance payment, as third-party reimbursement is affected by many variables.

If you have any questions regarding reimbursement for Optison, please call the GE Healthcare Reimbursement Hotline at 800 767 6664.


Click here for additional reimbursement resources.

Optison™ (Perflutren Protein-Type A Microspheres Injectable Suspension, USP)


BOXED WARNING: Serious Cardiopulmonary Reactions: Serious cardiopulmonary reactions, including fatalities, have occurred during or following perflutren-containing microsphere administration. Assess all patients for the presence of any condition that precludes Optison administration. In patients with pulmonary hypertension or unstable cardiopulmonary conditions, monitor vital sign measurements, electrocardiography, and cutaneous oxygen saturation during and for at least 30 minutes after Optison administration. Always have resuscitation equipment and trained personnel readily available.


INDICATIONS: Optison is indicated for use in patients with suboptimal echocardiograms to opacify the left ventricle and to improve the delineation of the left ventricular endocardial borders. The safety and efficacy of Optison with exercise or pharmacologic stress testing have not been established. CONTRAINDICATIONS: Do not administer Optison to patients with known or suspected (1) Right-to-left, bi-directional, or transient right-to-left cardiac shunts, or (2) Hypersensitivity to perflutren, blood, blood products, or albumin. Do not administer Optison by intra-arterial injection.

Please click here to see more Important Risk and Safety Information.

Prior to using Optison, please read the Full Prescribing Information.


CPT is a registered trademark of the American Medical Association

ICUS Sponsors

ICUS gratefully acknowledges its 2017 sponsors:






Contact ICUS

  • Address:  International Contrast Ultrasound Society
    c/o Dentons
    233 S. Wacker Drive, Suite 5900 Chicago, IL 60606-6361
  • Telephone: 202-408-6199

About ICUS

ICUS is the world’s only professional society exclusively devoted to contrast-enhanced ultrasound (CEUS) medical imaging technology.

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