Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo

Dynamic solid-state ultrasound contrast agent for monitoring pH fluctuations in vivo

March 23, 2020 — ACS Sensors
Abstract
The key challenge for in vivo biosensing is to design biomarker-responsive contrast agents that can be readily detected and monitored by broadly available biomedical imaging modalities. While a range of biosensors have been designed for optical, photoacoustic and magnetic resonance imaging (MRI) modalities, technical challenges have hindered the development of ultrasound biosensors, even though ultrasound is widely available, portable, safe, and capable of both surface and deep tissue imaging. Typically, contrast enhanced ultrasound imaging is (read more…)

Ultrasound Mediated Destruction of LMW-HA-Loaded and Folate-Conjugated Nanobubble for TAM Targeting and Reeducation

Ultrasound Mediated Destruction of LMW-HA-Loaded and Folate-Conjugated Nanobubble for TAM Targeting and Reeducation

March 23, 2020 — Dove Medical Press
Abstract
Purpose:  To synthesize and evaluate a novel folate-conjugated ultrasonic nanobubble (HA-FOL-NB) loading low-molecular-weight hyaluronic acid (LMW-HA) for specific tumor-associated macrophages (TAMs) targeting and reeducation.
Methods:  The characteristics, cytotoxicity, contrast-enhanced ultrasound imaging (CEUS), and targeting ability to TAMs of HA-FOL-NBs were investigated. The TAMs reprogramming function of HA-FOL-NBs combining ultrasound targeted nanobubble destruction was assessed as well.
Results:  HA-FOL-NBs (about 342 nm) showed remarkable contrast enhancement images, and higher targeting ability due to the folate to folate (read more…)

Ultrasound assessment of tumour oxygenation could guide cancer therapy

Ultrasound assessment of tumour oxygenation could guide cancer therapy

March 23, 2020 — Physicsworld
By Louisa Cockbill, Science writer
Pengfei Song, an assistant professor at the Beckman Institute at the University of Illinois, used ultrasound localization microscopy to visualize oxygen levels in tumours.
The centres of tumours often experience oxygen deprivation as the blood supply struggles to keep up with demand from uncontrollably proliferating tumour cells. Patients with tumours in this hypoxic state are known to have poorer outcomes, but until now, there’s been no viable non-invasive way to accurately measure tumour (read more…)

ASE Statement on Protection of Patients and Echocardiographic Service Providers During the 2019 Novel Coronavirus Outbreak

ASE Statement on Protection of Patients and Echocardiographic Service Providers During the 2019 Novel Coronavirus Outbreak

This important new guidance addresses the relatively high risk COVID-19 among healthcare workers, particularly through the kind of close contact involved in performing echocardiograms
ICUS appreciates the ASE’s careful attention to these urgent issues.  As the global pandemic continues to unfold, please send any additional recommendations to us at: info@icus-society.org. We wish you safety and good health as we continue to confront the challenges ahead.
To read the statement in full, please visit: http://icus-society.org/wp-content/uploads/2020/03/ASE-COVID-Statement-2020.pdf

Reality and possibilities in cardiology imaging

Reality and possibilities in cardiology imaging

March 17, 2020 — Dotmed/Healthcare Business News
By Tom Watson
Excerpt
Cardiac imaging is an active and growing area for clinical and technological innovations. While you can subdivide these technologies into large, highly complex market segments, the major cardiovascular solutions we will look at here are ultrasound (echocardiography), interventional fluoroscopic imaging (angiography), CT and MR.
I believe the transition of healthcare delivery from fee per procedure to a value-based model has likely suppressed activity and interest in many medical capital decisions. The ongoing merger (read more…)

New Treatment for Parkinson’s Disease Developed at NTHU

New Treatment for Parkinson’s Disease Developed at NTHU

March 11, 2020 — Business Wire
A research team led by Yu-Chun Lin and Chih-kuang Yeh of NTHU has expanded application of ultrasound to the treatment of Parkinson’s disease.
HSINCHU, Taiwan–Ultrasound is widely used for conducting physical examinations, and plans are underway for expanding its application to the treatment of Parkinson’s disease, dementia, and diabetes. A research team at National Tsing Hua University led by Associate Professor Yu-Chun Lin of the Institute of Molecular Medicine and Professor Chih-kuang Yeh of the Department (read more…)

Role of intraoperative ultrasound in robotic-assisted radical nephrectomy with inferior vena cava thrombectomy in renal cell carcinoma

Role of intraoperative ultrasound in robotic-assisted radical nephrectomy with inferior vena cava thrombectomy in renal cell carcinoma

March 5, 2020 — World Journal of Urology
Abstract
Purpose
To determine the impact of intraoperative ultrasound on robotic-assisted radical nephrectomy with inferior vena cava (IVC) tumor thrombectomy in renal cell carcinoma (RCC).
Methods
We retrospectively analyzed intraoperative records of 27 patients with RCC and invasion of the IVC who underwent robotic-assisted nephrectomy with tumor thrombectomy at our center between December 2017 and July 2018. Diagnostic utility and impact of intraoperative transesophageal echocardiography (TEE), intraoperative robotic-assisted ultrasonography, and intraoperative contrast-enhanced ultrasound (CEUS) on surgical management (read more…)

Implementing a Liver Contrast Program in the Sonography Laboratory – A White Paper

Implementing a Liver Contrast Program in the Sonography Laboratory – A White Paper

Mar 4, 2020 — Journal of Diagnostic Medical Sonography
The Society of Diagnostic Medical Sonography (SDMS) is pleased to announce the publication of a white paper on implementing a liver contrast program in the sonography laboratory in the January/February 2020 issue of the
In 2016 the Food and Drug Administration (FDA) approved contrast-enhanced ultrasound (CEUS) to image and characterize liver lesions as benign or malignant using gray-scale sonography. The technique includes the intravenous (IV) administration of a gas microbubble that the vascular (read more…)

Contrast enhanced ultrasound: comparing a novel modality to MRI to assess for bowel disease in pediatric Crohn’s patients

Contrast enhanced ultrasound: comparing a novel modality to MRI to assess for bowel disease in pediatric Crohn’s patients

April 5, 2020 — Translational Gastroenterology and Hepatology
Abstract
Background:
To demonstrate the feasibility and reliability of a novel imaging modality, contrast enhanced ultrasound (CEUS), in evaluating for distal small bowel inflammation in pediatric Crohn’s disease (CD), and compare this to concurrently obtained magnetic resonance imaging (MRI) findings.
Methods:
Pediatric patients diagnosed with or having suspicion of CD with small bowel involvement, whose disease merited imaging with an MRI, concurrently underwent imaging with CEUS. We assessed the ability of CEUS to demonstrate distal small bowel (read more…)

Contrast-Enhanced Ultrasound of Congenital and Infantile Hemangiomas: Preliminary Results From a Case Series

Contrast-Enhanced Ultrasound of Congenital and Infantile Hemangiomas: Preliminary Results From a Case Series

February 26, 2020 — American Journal of Roentgenology
Abstract:
OBJECTIVE. The contrast-enhanced ultrasound (CEUS) imaging features of hepatic vascular tumors in infants, including infantile hemangioma (IH) and congenital hemangioma (CH), are not well reported. Frequent inaccurate use of lesion terminology in the literature has created diagnostic confusion. The purpose of this study is to describe the CEUS features of IH and CH.
MATERIALS AND METHODS. Ten patients, ranging in age from 8 days to 16 months, with hepatic vascular tumors were included for (read more…)