Targeted nanoparticles for HER2-positive breast cancer

Targeted nanoparticles for HER2-positive breast cancer

April 5, 2019 — Dove Medical Press
Targeted Fe-doped silica nanoparticles as a novel ultrasound–magnetic resonance dual-mode imaging contrast agent for HER2-positive breast cancer
Abstract
Background: Multimodal contrast agents with low toxicity and targeted modification have opened up new possibilities for specific imaging of breast cancer and shown broad application prospects in biomedicine and great potential for clinical transformation. In this work, a potential multifunctional imaging agent was developed by doping Fe into hollow silica nanoparticles (HS-Fe NPs), followed by modification with specific (read more…)

Contrast-Enhanced Ultrasound Offers Enhanced Diagnostic Sensitivity for Diagnosis of Renal Cancer

Contrast-Enhanced Ultrasound Offers Enhanced Diagnostic Sensitivity for Diagnosis of Renal Cancer

March 28, 2019 — Journal of Ultrasound Medicine
Diagnostic Imaging
CEUS for Renal Cancer Diagnosis
A new meta-analysis published in the Journal of Ultrasound Medicine suggests that contrast-enhanced ultrasound (CEUS) may offer more sensitivity and specificity for the diagnosis of renal cancer than contrast-enhanced computer tomography (CECT).
Researchers from China compared the diagnostic accuracy of CEUS to CECT in order to evaluate patients for renal cancer. The researchers reviewed data sets from twenty-two studies published before 2017, performing a meta-analysis on a variety of (read more…)

ICUS  – 2019 ICUS-sponsored educational courses

ICUS  – 2019 ICUS-sponsored educational courses

Essentials of CEUS: The Basics and Beyond
Orlando — April 10, 2019
Abdominal CEUS
Hilton Orlando Bonnet Creek
Note: Remote attendance via the internet with livestreaming also available
* Register now for in-person attendance at: www.regonline.com/ceusessentialsorlando
* Register for remote attendance at: www.regonline.com/ceusessentialsorlando-livestream
For full details including agenda and faculty, please visit:
http://icus-society.org/ceus-education-and-training-orlando-2019/

Injury Recovery, Noninvasive Ultrasounds & Ask the Doctor

Injury Recovery, Noninvasive Ultrasounds & Ask the Doctor

March 22, 2019 – Radio.com – Sports Medicine Weekly
https://670thescore.radio.com/media/audio-channel/injury-recovery-noninvasive-ultrasounds-ask-doctor
Physical Therapist and Program Head – Movement Performance Project at Athletico Physical Therapy- Carson Lux shares 30 years of experience, graduating from the University of Evansville in 1989. He played HS football, basketball, and baseball, collegiate and studied Aikido and subsequently has undergone multiple orthopedic surgeries as a result of his own athletic career and has a unique understanding of what athletes must endure to return to their sports.
In this segment (read more…)

Contrast Enhanced Ultrasound and Endovascular Aortic Repair 2019 – 10th International Workshop on CEUS and EVAR

Contrast Enhanced Ultrasound and Endovascular Aortic Repair 2019 – 10th International Workshop on CEUS and EVAR

EFSUMB
May 16th, 2019
Ludwig Maximilian University, Munich
For full details, please visit: http://icus-society.org/wp-content/uploads/2019/03/CEUS-München-2019-details.pdf
For registration, please visit: http://icus-society.org/wp-content/uploads/2019/03/CEUS-München-2019-registration.pdf

A multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions

A multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions

March 15, 2019 – Dovepress
Abstract
Purpose: To evaluate a classification model of contrast-enhanced ultrasound (CEUS) and examine the characteristics of patients with false-negative diagnosis.
Patients and methods: A retrospective secondary analysis of a multicenter trial of CEUS for breast cancer diagnosis (from August 2015 to April 2017) was undertaken. Patients (n=1,023) with Breast Imaging Reporting and Data System 4–5 lesions on B-mode ultrasound underwent CEUS. Pathological diagnoses were available from surgical or biopsy specimens for correlation. Lesion maximum diameter (LMD), distance to (read more…)

Petition calls for removal of ‘black box’ designation for ultrasound contrast agents

Petition calls for removal of ‘black box’ designation for ultrasound contrast agents

March 13, 2019 – DOTMed
HealthCare Business Daily News
By John R. Fischer , Staff Reporter
Ultrasound societies across America and worldwide are calling for the FDA to remove its “black box” designation for ultrasound contrast agent labels.
Expressing their reasoning in a Citizen Petition filed by the International Contrast Ultrasound Society (ICUS), the groups argue that scientific research and studies support UCAs as safe diagnostic imaging products and that the black box misrepresents risks, leading providers to refrain from using the agents in (read more…)

Groups Pushing For FDA To Remove Boxed Warning From Ultrasound Contrast Agents.

Groups Pushing For FDA To Remove Boxed Warning From Ultrasound Contrast Agents.

Mar 7, 2019 – RSNA – RadiologyDaily
HEALTH POLICY
The Radiology Business Journal (3/6, Walter) reports, “The International Contrast Ultrasound Society (ICUS) is once again pushing the FDA to eliminate the” boxed “warning from ultrasound contrast agents (UCAs), detailing its stance in a petition.” The article adds, “According to the ICUS, the” boxed “warning is appropriate when FDA-approved products carry a significant risk, but research has shown that UCAs put patients at no such risk.”
HealthImaging (3/6, O’Connor) reports, “A host of ultrasound (read more…)

Ultrasound Societies Urge FDA to Remove Black Box Warning on Contrast Agents

Ultrasound Societies Urge FDA to Remove Black Box Warning on Contrast Agents

March 7, 2019 – Imaging Technology News
Citizen petition argues that current research has demonstrated ultrasound contrast agents safe and effective
National and international ultrasound societies are urging the U.S. Food and Drug Administration to remove the “black box” from ultrasound contrast agent (UCA) labels.
“UCAs are among the safest diagnostic imaging products available,” according to a citizen petition filed by the International Contrast Ultrasound Society (ICUS).
UCAs are used worldwide to enhance diagnostic ultrasound scans, according to the petition, which cited an extensive (read more…)

Drug delivery System Works Like Paint by ‘Numbers’

Drug delivery System Works Like Paint by ‘Numbers’

Futurity.org
A new drug delivery system, called cavitation dose painting, would make getting drugs where they need to go more like “paint by numbers” and less like paintball.
March 1, 2019
Source: Washington University in St. Louis
Original Study DOI: 10.1038/s41598-019-39090-
If the drug needs to enter the bloodstream and circulate throughout your body for treating disease wherever it may be, the paintball-like delivery system may work, but it won’t work for targeted and precise drug delivery.
A technique more like “painting by numbers,” would (read more…)