Drug delivery System Works Like Paint by ‘Numbers’

Drug delivery System Works Like Paint by ‘Numbers’

Futurity.org
A new drug delivery system, called cavitation dose painting, would make getting drugs where they need to go more like “paint by numbers” and less like paintball.
March 1, 2019
Source: Washington University in St. Louis
Original Study DOI: 10.1038/s41598-019-39090-
If the drug needs to enter the bloodstream and circulate throughout your body for treating disease wherever it may be, the paintball-like delivery system may work, but it won’t work for targeted and precise drug delivery.
A technique more like “painting by numbers,” would (read more…)

ICUS Education and Training CEUS Essentials – The Basics and Beyond

ICUS Education and Training CEUS Essentials – The Basics and Beyond

Abdominal CEUS in Orlando, FL
Wednesday, April 10, 2019 — Immediately following AIUM
Hilton Orlando Bonnet Creek
14100 Bonnet Creek Resort Ln, Orlando, FL 32821
Host: Stephanie Wilson, MD
Registration now open – for in-person or remote attendance!
Program description
Attendees at this course will:

Perform a standard CEUS examination of the liver or other chosen organ
Recognize the fundamental observations on CEUS to determine if a liver mass is malignant
Interpret the enhancement patterns for specific diagnosis of focal liver masses
Realize the broad reaching applications for CEUS in diagnostic (read more…)

Ultrasound Societies Urge FDA to Remove “Black Box” on Ultrasound Contrast Agents

Ultrasound Societies Urge FDA to Remove “Black Box” on Ultrasound Contrast Agents

Mar 5, 2019
CHICAGO – (Business Wire) – National and international ultrasound societies are urging the Food and Drug Administration to remove the “black box” from ultrasound contrast agent (UCA) labels.
“UCAs are among the safest diagnostic imaging products available,” according to a Citizen Petition filed by the International Contrast Ultrasound Society (ICUS).
UCAs are used worldwide to enhance diagnostic ultrasound scans, according to the Petition, which cited an extensive body of favorable safety data that was not available in 2007 when the (read more…)

Groups continue push for FDA to remove ‘black box’ warning from ultrasound contrast agents

Groups continue push for FDA to remove ‘black box’ warning from ultrasound contrast agents

March 06, 2019 – Radiology Business
By Michael Walter
The International Contrast Ultrasound Society (ICUS) is once again pushing the FDA to eliminate the “black box” warning from ultrasound contrast agents (UCAs), detailing its stance in a petition supported by several other medical societies. The ICUS also pushed the FDA to remove these warnings back in September 2018.
“It is clear to all who work in the field on a daily basis that the black box harms patient care by misrepresenting risk and (read more…)

Ultrasound societies want the FDA to remove contrast label warning

Ultrasound societies want the FDA to remove contrast label warning

March 06, 2019 – HealthImaging
By Matt O’Connor
The International Contrast Ultrasound Society (ICUS) is again urging the FDA to remove the “black box” warning from ultrasound contrast agent (UCA) labels, following its filing of a September 2018 citizen petition with the FDA.
“It is clear to all who work in the field on a daily basis that the black box harms patient care by misrepresenting risk and inappropriately deterring the use of UCAs when they are medically indicated,” said Steven Feinstein, co-president (read more…)

Ultrasound Societies Urge FDA to Remove “Black Box” on Ultrasound Contrast Agents

Ultrasound Societies Urge FDA to Remove “Black Box” on Ultrasound Contrast Agents

Mar 05, 2019 – BioSpace 
Source: Business Wire
CHICAGO–(BUSINESS WIRE)– National and international ultrasound societies are urging the Food and Drug Administration to remove the “black box” from ultrasound contrast agent (UCA) labels.
“UCAs are among the safest diagnostic imaging products available,” according to a Citizen Petition filed by the International Contrast Ultrasound Society (ICUS).
UCAs are used worldwide to enhance diagnostic ultrasound scans, according to the Petition, which cited an extensive body of favorable safety data that was not available in 2007 when (read more…)

New Polylactic Acid Multifunctional Ultrasound Contrast Agent Based on Graphene Oxide as the Carrier of Targeted Factor and Drug Delivery

New Polylactic Acid Multifunctional Ultrasound Contrast Agent Based on Graphene Oxide as the Carrier of Targeted Factor and Drug Delivery

Mar 4, 2019 – ACS Omega
Abstract
In recent years, the development of ultrasound contrast agents has encouraged their use as a drug system for diagnosis and therapy. In this paper, polylactic acid (PLA) composite microbubbles (FA/DOX/GO/DOX/PLA) were prepared with graphene oxide (GO) as a carrier of the targeted factor folic acid (FA) and doxorubicin (DOX) by the multiple emulsification–solvent evaporating process. Appearance, particle size, and zeta potential of PLA composite microbubbles were characterized by using a nanoparticle size analyzer and transmission (read more…)

A new method for precision drug delivery: Painting

A new method for precision drug delivery: Painting

February 27, 2019 – Science Daily
Researchers are integrating  ultrasound imaging with ultrasound therapy to pave the way for a new kind of drug delivery
Source: Washington University in St. Louis
Summary:
Researchers are one step closer to delivering precise amounts of medication to exact location, repurposing an existing imaging ”painting” method.
Full Story:
If traditional drug delivery were a type of painting, it might be akin to paintball. With good aim, a majority of the paint ends on the bullseye, but it also drips and (read more…)

Radiology Reimbursement in 2019

Radiology Reimbursement in 2019

Feb 4, 2019 – Diagnostic Imaging
By: Whitney J. Palmer
For the third year running, radiology is seeing a lull in coding and reimbursement changes.
But, while there are relatively few alternations to how you should code for—and will get paid for—your services, that doesn’t mean there aren’t things you should pay attention to this year to maintain a healthy bottom line. And, according to industry leaders, you can also take active steps in this direction.
Embrace MIPS changes
In a downgrade from last year, (read more…)

CEUS Guidance for Interventional Procedures

CEUS Guidance for Interventional Procedures

Feb 4, 2019 – Journal of Ultrasound in Medicine
Abstract
Since its introduction, contrast enhanced ultrasound (CEUS) has gained an important role in the diagnosis and management of abdominal and pelvic diseases. Contrast enhanced ultrasound can improve lesion detection rates as well as success rates of interventional procedures when compared to conventional ultrasound alone. Additionally, CEUS enables the interventionalist to assess the dynamic enhancement of different tissues and lesions, without the adverse effects of contrast‐enhanced computed tomography, such as exposure to ionizing (read more…)